maalox extra strength ingredients
maalox extra strength ingredients
Increased urine alkalinity also can inhibit the conversion of methenamine to formaldehyde, which is the active bacteriostatic form; concurrent use of methenamine and urinary alkalizers is not recommended. Prescription prices may vary from pharmacy to pharmacy and are subject to change. 
If aluminum-based antacids are used on a regular basis, an alternative to pseudoephedrine may be considered. Because vitamin D analogs can increase serum magnesium concentrations, concomitant use should be avoided, if possible, in patients with chronic renal failure. As these compounds enter the small intestine, they react with bicarbonate, forming magnesium carbonate and calcium carbonate, which are insoluble. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. Gefitinib exposure is affected by gastric pH. The chemical structure of these GI drugs that contain polyvalent cations, such as magnesium hydroxide, can bind dolutegravir in the GI tract. If drug therapy is required for heartburn (pyrosis), dyspepsia, or reflux, experts usually recommend that first-line therapy consist of nonsystemically absorbed medications, including antacids, which offer little, if any, risk to the fetus. Penicillamine: (Moderate) Because penicillamine chelates heavy metals, it is possible that antacids could reduce penicillamine bioavailability, which can decrease the therapeutic effects of penicillamine. If aluminum-based antacids are used on a regular basis, an alternative to pseudoephedrine may be considered. Quinidine: (Major) Alkalinizing agents such as antacids can increase renal tubular reabsorption of quinidine by alkalinizing the urine; higher quinidine serum concentrations and quinidine toxicity are possible. The accumulation of aluminum can lead to dialysis encephalopathy, dialysis osteomalacia, or 'dialysis dementia' (impaired cognition). The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice. To minimize drug interactions, administer ursodiol at least 1 hour before or at least 2 hours after the aluminum-based antacid. Acetaminophen; Chlorpheniramine: (Minor) Antacids can delay the oral absorption of acetaminophen, but the interactions are not likely to be clinically significant as the extent of acetaminophen absorption is not appreciably affected. (Moderate) Concurrent administration of rilpivirine and antacids may significantly decrease rilpivirine plasma concentrations, potentially resulting in treatment failure. However, due to the fact that simethicone is not absorbed systemically, it seems unlikely that simethicone would be excreted in the milk of breast-feeding women. Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate: (Moderate) Separate administration of elvitegravir and antacids by at least 2 hours. Simethicone-containing products should be used in pregnancy only when the maternal benefits outweigh the risks.Following administration of aluminum hydroxide; magnesium hydroxide; simethicone, neither aluminum nor magnesium enter breast milk significantly, and no problems have been reported with the use of antacids during breast-feeding. Coadministration of aluminum/magnesium hydroxide and bazedoxifene decreased Cmax of bazedoxifene by 8% and increased AUC of bazedoxifene by 7%. Closely monitor patients for changing analgesic requirements or adverse events. More hydrogen ions are lost from the stomach than are lost from the intestine, resulting in metabolic alkalosis. Administer cholic acid at least 1 hour before or 4 to 6 hours (or the maximal interval possible) after an aluminum-based antacids. This is of primary significance in patients with renal failure. Patients at increased risk of aluminum accumulation include patients with renal impairment or renal failure. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. The chemical structure of these antacids contain aluminum which can bind dolutegravir in the GI tract. Although the exact mechanism is not known, theoretically it may be due to alterations in gastric pH. Amprenavir: (Moderate) Coadministration with antacids decreases amprenavir plasma concentrations. Dihydrocodeine; Guaifenesin; Pseudoephedrine: (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. If an antacid must be used while a patient is taking cefuroxime, administer the oral dosage of cefuroxime at least 1 hour before or 2 hours after the antacid. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. In a small study involving 6 healthy subjects and 6 peptic ulcer patients, cimetidine increased the Cmax and AUC of mefloquine. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. If aluminum-based antacids are used on a regular basis, an alternative to pseudoephedrine may be considered. In-vitro studies suggest that calcium and magnesum cations exert their deleterious effect on replacement enzyme therapy by formation of poorly soluble calcium or magnesium soaps and precipitation of glycine conjugated bile salts. General Administration InformationFor storage information, see the specific product information within the How Supplied section.Route-Specific AdministrationOral AdministrationNOTE: The composition of available products (i.e., chewable tablets and oral suspension) is variable. Norfloxacin: (Major) Administer magnesium hydroxide at least 2 hours before or 2 hours after norfloxacin. To decrease the risk of virologic failure, avoid use of antacids for at least 2 hours before and at least 4 hours after administering rilpivirine. Dosage should be modified depending on clinical response and degree of renal impairment. Gastric acidity is an essential requirement for adequate absorption of levothyroxine. Hydrocodone: (Minor) Concurrent use of hydrocodone with strong laxatives that rapidly increase gastrointestinal motility, such as magnesium hydroxide, may decrease hydrocodone absorption. Pharmacokinetics:Aluminum hydroxide; magnesium hydroxide; simethicone is administered orally.-Aluminum Hydroxide: Aluminum hydroxide is slowly solubilized in the stomach and reacts with hydrochloric acid in the stomach to produce aluminum chloride and water. The liquid product may be stored in the refrigerator to improve taste. This can cause low phosphate levels, especially if you use this medication in large doses and for a long time. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. Do not take magnesium hydroxide within 2 hours of taking risedronate. Atorvastatin; Ezetimibe: (Minor) Antacids may decrease the peak plasma concentration (Cmax) of total ezetimibe by 30%. Azithromycin: (Moderate) Separate administration of immediate-release azithromycin and aluminum- and magnesium-containing antacids by 2 hours. If aluminum-based antacids are used on a regular basis, an alternative to pseudoephedrine may be considered. Antacids containing alkalinizing agents such as sodium bicarbonate can alkalinize the urine, thereby decreasing the effectiveness of methenamine by increasing the amount of non-ionized drug available for renal tubular reabsorption. If you have any questions, ask your doctor or pharmacist. In another study, antacids have been shown to reduce the AUC of atenolol by 33%. Monitor clinical response, and adjust propranolol dosage if needed to attain therapeutic goals. Closely monitor patients for changing analgesic requirements or adverse events. One case of grand mal seizure has been reported in a patient with chronic hypocalcemia of renal failure who was given sodium polystyrene with magnesium hydroxide as laxative. Tell your doctor right away if you have any of the following symptoms of low phosphate: loss of appetite, unusual tiredness, muscle weakness. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. Carbinoxamine; Pseudoephedrine: (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. Drug information is sourced fromGSDD (Gold Standard Drug Database )provided by Elsevier. Manufacturer Coupons and Offers Available. Gastric acidity is an essential requirement for adequate absorption of levothyroxine. By declining you will be logged out of your account, ALMACONE-2 (Generic for MAALOX MAXIMUM STRENGTH) Monographs, QTY 355 400-400-40 Oral Suspension Near 77381. Coadministration may impair absorption of demeclocycline which may decrease its efficacy. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. It may be used alone or with other medications that lower acid production (including H2 blockers such as cimetidine/ranitidine and proton pump inhibitors such as omeprazole).If you are self-treating with this medication, carefully read the package instructions before you start using this product to be sure it is right for you. However, since deferiprone has the potential to bind polyvalent cations (e.g., iron, aluminum, and zinc), allow at least a 4-hour interval between deferiprone and other medications or dietary supplements containing these polyvalent cations. In general, it would be illogical to concurrently administer these drugs at the same time. Allopurinol: (Minor) Aluminum hydroxide decreases the oral bioavailability of allopurinol, possibly by inhibiting gastrointestinal absorption of allopurinol. Coadministration may impair absorption of omadacycline which may decrease its efficacy. A very serious allergic reaction to this drug is rare. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. Glipizide; Metformin: (Moderate) Antacids have been reported to increase the absorption of glipizide, enhancing its hypoglycemic effects. Phosphorus: (Moderate) Phosphate may bind magnesium salts and magnesium-containing antacids (e.g., magnesium carbonate, magnesium hydroxide) may limit phosphorus absorption or phosphorus may limit magnesium absorption. Delafloxacin absorption may be reduced as quinolone antibiotics can chelate with divalent or trivalent cations. Norethindrone; Ethinyl Estradiol; Ferrous fumarate: (Moderate) Doses of antacids and iron should be taken as far apart as possible to minimize the potential for interaction. Hydroxychloroquine: (Moderate) Hydroxychloroquine absorption may be reduced by antacids as has been observed with the structurally similar chloroquine. Closely monitor patients for changing analgesic requirements or adverse events. Sodium Citrate; Citric Acid: (Contraindicated) Avoid coadministration of antacids with citrate salts since increased absorption of aluminum can occur. At higher pH values, iron is more readily ionized to its ferric state and is more poorly absorbed. Hydrocodone; Phenylephrine: (Minor) Concurrent use of hydrocodone with strong laxatives that rapidly increase gastrointestinal motility, such as magnesium hydroxide, may decrease hydrocodone absorption. (Minor) Concurrent use of hydrocodone with strong laxatives that rapidly increase gastrointestinal motility, such as magnesium hydroxide, may decrease hydrocodone absorption. Didanosine, ddI: (Minor) The side effects associated with aluminum hydroxide may potentially be increased during concurrent use with didanosine, ddI because some ddI products also contain similar antacid ingredients. Avoid antacids within 1 hour before or after the bisacodyl dosage. Follow all the directions on the product package or use as directed by your doctor. Cetirizine; Pseudoephedrine: (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. Levofloxacin absorption may be reduced as quinolone antibiotics can chelate with divalent or trivalent cations. Examples of compounds that may interfere with quinolone bioavailability include antacids that contain magnesium hydroxide. Decreased absorption of mycophenolate (possible chelation) is the likely etiology for reduced systemic exposure. Atenolol: (Minor) Aluminum hydroxide antacids have been reported to decrease atenolol mean peak concentrations by about 20% and the AUC of atenolol by 57%. Acalabrutinib: (Moderate) Separate the administration of acalabrutinib and antacids by at least 2 hours if these agents are used together. Monitor clinical response, and adjust propranolol dosage if needed to attain therapeutic goals. Iron: (Moderate) Doses of antacids and iron should be taken as far apart as possible to minimize the potential for interaction. Otherwise, call a poison control center right away. Concomitant use of oral budesonide and antacids, milk, or other drugs that increase gastric pH levels can cause the coating of the granules to dissolve prematurely, possibly affecting release properties and absorption of the drug in the duodenum. Examples of compounds that may interfere with quinolone bioavailability include antacids that contain aluminum hydroxide. Antacids can impair the absorption of ketoconazole. Monitor serum potassium levels to determine the need for potassium supplementation and/or alteration in drug therapy. Gastric acidity is an essential requirement for adequate absorption of levothyroxine. 
Keep all regular medical and laboratory appointments. Cabotegravir; Rilpivirine: (Moderate) Administer antacids at least two hours before or four hours after taking oral cabotegravir. If an antidiarrheal medication is needed, it would be wise to temporarily discontinue use of agents with laxative effects. However, no dosage guidelines are available.CrCl 10-25 mL/min: Patients with renal impairment may be at risk of accumulating aluminum and magnesium. Closely monitor patients for changing analgesic requirements or adverse events. Chelation of divalent cations with levofloxacin is less than with other quinolones. Simethicone is not known to interfere with gastric secretion or nutrient absorption.-Special PopulationsRenal Impairment-Magnesium Hydroxide: In patients with significant renal impairment, the amount of magnesium absorbed from aluminum hydroxide; magnesium hydroxide; simethicone products is significant enough to produce hypermagnesemia. If aluminum-based antacids are used on a regular basis, an alternative to pseudoephedrine may be considered. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. Sumatriptan; Naproxen: (Minor) Concomitant administration of antacids can delay the absorption of naproxen. *By signing up I am agreeing to receive price drop alert emails. If antacids must be used while a patient is taking glyburide, give the glyburide at least 2 hours prior to the antacid. Gemifloxacin absorption may be reduced as quinolone antibiotics can chelate with divalent or trivalent cations. (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. 
Chlorpheniramine; Hydrocodone; Phenylephrine: (Minor) Concurrent use of hydrocodone with strong laxatives that rapidly increase gastrointestinal motility, such as magnesium hydroxide, may decrease hydrocodone absorption. If you are taking the chewable tablets, chew thoroughly before swallowing, then drink a full glass of water (8 ounces or 240 milliliters). The chemical structure of these antacids contains aluminum or magnesium which can bind cabotegravir in the GI tract. Administration of delavirdine and antacids should be separated by at least 1 hour. Coadministration interferes with cefditoren absorption causing a decrease in the Cmax and AUC. Properly discard this product when it is expired or no longer needed. Acetaminophen; Pamabrom; Pyrilamine: (Minor) Antacids can delay the oral absorption of acetaminophen, but the interactions are not likely to be clinically significant as the extent of acetaminophen absorption is not appreciably affected. Antacids may decrease the absorption of oral iron preparations. Methenamine: (Major) The therapeutic action of methenamine requires an acidic urine. This is of primary significance in patients with renal failure. Zalcitabine, ddC: (Moderate) The absorption of zalcitabine is moderately reduced when coadministered with aluminum hydroxide. Sofosbuvir; Velpatasvir; Voxilaprevir: (Moderate) Separate the use of antacids and velpatasvir administration by 4 hours. Mesalamine, 5-ASA: (Moderate) Do not coadminister mesalamine extended-release capsules (Apriso) with antacids. The range of the discounts will vary depending on the type of prescription and the pharmacy chosen. Coadministration may impair absorption of tetracycline which may decrease its efficacy. Examples of compounds that may interfere with quinolone bioavailability include antacids that contain magnesium hydroxide. Antacids may decrease the absorption of digoxin. Loop diuretics: (Moderate) Loop diuretics may increase the risk of hypokalemia especially in patients receiving prolonged therapy with laxatives. Ofloxacin absorption may be reduced as quinolone antibiotics can chelate with divalent or trivalent cations. (Moderate) The chronic use of aluminum-containing antacids (e.g., aluminum hydroxide-containing antacids) for hyperphosphatemia in conjunction with vitamin D can lead to aluminum retention and possible toxicity. Chlorpheniramine; Pseudoephedrine: (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. Atazanavir: (Major) It is recommended that antacids not be given at the some time as atazanavir because of potential interference with absorption of atazanavir. (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. Nilotinib displays pH-dependent solubility with decreased solubility at a higher pH; therefore, concomitant use of nilotinib and antacids may result in decreased bioavailability of nilotinib. At higher pH values, iron is more readily ionized to its ferric state and is more poorly absorbed. 
Loratadine; Pseudoephedrine: (Minor) It appears that antacids containing aluminum hydroxide may increase pseudoephedrine plasma concentrations. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. (Minor) Monitor for an increase in capecitabine-related adverse reactions if coadministration with magnesium hydroxide is necessary. Patients who are dehydrated, fluid restricted, or have preexisting decreased bowel motility are predisposed to developing constipation or GI obstruction due to the aluminum in aluminum hydroxide; magnesium hydroxide; simethicone. If aluminum-based antacids are used on a regular basis, an alternative to pseudoephedrine may be considered. Medical Security Card Company, LLC All Rights Reserved. Ofloxacin absorption may be reduced as quinolone antibiotics can chelate with divalent or trivalent cations. 
In another study, antacids have been shown to reduce the AUC of atenolol by 33%. It is also used to relieve symptoms of extra gas such as belching, bloating, and feelings of pressure/discomfort in the stomach/gut. Taking these drugs simultaneously may result in reduced bioavailability of dolutegravir. This interaction can be avoided by separating the administration of pseudoephedrine and antacids by 1 to 2 hours. Due to the formation of ionic complexes in the gastrointestinal tract, simultaneous administration results in lower elvitegravir plasma concentrations. ALUMINUM HYDROXIDE; MAGNESIUM HYDROXIDE; SIMETHICONE (a LOO mi num hye DROX ide; mag NEE zhum hye DROX ide; sye METH i kone) is an antacid and antigas medicine. If it is near the time of the next dose, skip the missed dose. Simultaneous oral administration should be avoided when feasible; separate dosing by at least 2 hours to limit an interaction. You can mix your dose with a little water if needed. Levofloxacin absorption may be reduced as quinolone antibiotics can chelate with divalent or trivalent cations. Pancrelipase: (Major) The effectiveness of gastrointestinal enzymes can be diminished with concurrent administration of antacids.
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